Single Cell

Computational models

• Hodgkin-Huxley model

• Detailed model of an L5 cortical neuron (TBA on publication)

• Equivalent model of an L5 cortical neuron with reduced morphology (TBA on publication)

Principles of single cell modeling and tuning

• Tutorials on single cell properties

• Tutorial: tune cells from AllenDB

• Guidelines for manual tuning of channel conductances (TBA on ACT publication)

• Guidelines for manual tuning of synapses and synaptic inputs (detailed cell)

• Guidelines for building equivalent cells with reduced morphology

• Biophysics of detailed cells

Automated tuning

• Automatic cell tuner (TBA on ACT publication)

• Automatic synaptic input tuner (TBA on publication)

Packages

We use the following packages for single cell modeling:

• NEURON (also see MIT NEURON tutorial)

• BMTK

Datasets

• CRCNS: hc-3. Spike recordings from the rat hippocampal areas.

• Buzsaki lab datasets. Spike and LFP recordings from rodents.

• The DANDI Archive. Various neurophysiology recordings.